- smoking(니코틴-혈관 spasm)
- dyslipidemia(이상지질혈증) : LDL↑, Chol↑, HDL↓
- DM
- imparied renal function
- obesity
- inactivity
- age(M 55↑, F 65↑)
- CAD
-caffeine
- Na↑
- stress
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