- age↑
- white
- family Hx(genetic factor : BRCA, BRCA2)
- early menarch(12세), late menopause(55세)
- pre. breast, uterine, ovarian Ca
- nulliparity(임신X), late 1st childbirth(30세↑)
- obesity, radiation, alcohol, smoking
- HRT(hormone replacement therapy), oral pill
- menopause
- DES(estrogen)
- densetissue breast
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